This infographic illustrates our research question: Does PM2.5 accelerate renal aging? And how? PM2.5 are fine particles in the air that can penetrate our body and reach our kidneys. We hypothesize that PM2.5 interferes with the same mechanisms of aging in the kidneys: epigenetic changes, oxidative stress and inflammation. These mechanisms synergize to induce premature aging of the kidney. We are testing this hypothesis using various techniques and models.